{"id":2134,"date":"2019-04-29T15:02:02","date_gmt":"2019-04-29T07:02:02","guid":{"rendered":"https:\/\/www.merieuxnutrisciences.com.cn\/?p=2134"},"modified":"2023-04-24T09:51:35","modified_gmt":"2023-04-24T01:51:35","slug":"intestinal-microflora-tips","status":"publish","type":"post","link":"https:\/\/www.merieuxnutrisciences.com.cn\/?p=2134","title":{"rendered":"\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u6d45\u8c08"},"content":{"rendered":"<div class=\"taxonomy-post_tag wp-block-post-terms\"><a href=\"https:\/\/www.merieuxnutrisciences.com.cn\/?tag=%E4%B8%B4%E5%BA%8A%E7%A0%94%E7%A9%B6\" rel=\"tag\">\u4e34\u5e8a\u7814\u7a76<\/a><span class=\"wp-block-post-terms__separator\">, <\/span><a href=\"https:\/\/www.merieuxnutrisciences.com.cn\/?tag=%E6%A2%85%E9%87%8C%E5%9F%83%E6%A3%80%E6%B5%8B\" rel=\"tag\">\u6885\u91cc\u57c3\u68c0\u6d4b<\/a><span class=\"wp-block-post-terms__separator\">, <\/span><a href=\"https:\/\/www.merieuxnutrisciences.com.cn\/?tag=%E6%A2%85%E9%87%8C%E5%9F%83%E8%90%A5%E5%85%BB%E7%A7%91%E5%AD%A6\" rel=\"tag\">\u6885\u91cc\u57c3\u8425\u517b\u79d1\u5b66<\/a><span class=\"wp-block-post-terms__separator\">, <\/span><a href=\"https:\/\/www.merieuxnutrisciences.com.cn\/?tag=%E8%82%A0%E9%81%93%E5%BE%AE%E7%94%9F%E7%89%A9%E7%BE%A4\" rel=\"tag\">\u80a0\u9053\u5fae\u751f\u7269\u7fa4<\/a><\/div>\n\n<p><span style=\"color: #0d3978;\"><strong><span style=\"font-size: 14px;\">\u4ec0\u4e48\u662f\u80a0\u9053\u5fae\u751f\u7269\u7fa4\uff1f<\/span><\/strong><\/span><\/p>\n<p><span style=\"font-size: 14px;\">\u7531\u7ea610-100\u4e07\u4ebf\u4e2a\u5171\u751f\u7684\u5fae\u751f\u7269\u7ec6\u80de\u7ec4\u6210\u7684\u5fae\u751f\u7269\u7fa4\u904d\u5e03\u4eba\u4f53\u5404\u4e2a\u90e8\u4f4d\uff0c\u5fae\u751f\u7269\u7fa4\u5305\u542b\u5fae\u751f\u7269\u7ec6\u80de\u7684\u6240\u6709\u57fa\u56e0\u7ec4\u7fa4\u3002\u5176\u4e2d\uff0c\u7ea670%\u7684\u5fae\u751f\u7269\u7fa4\u90fd\u5b58\u5728\u4e8e\u80a0\u9053\u73af\u5883\u4e2d\u3002\u80a0\u5185\u4e3b\u5bfc\u5fae\u751f\u7269\u4e3a\u539a\u58c1\u83cc\u95e8\uff0c\u62df\u6746\u83cc\u548c\u53d8\u5f62\u6746\u83cc\uff0c\u4ee5\u53ca\u8f83\u5c11\u6bd4\u4f8b\u7684\u653e\u7ebf\u83cc\u3002\u00a0<\/span><\/p>\n<p><span style=\"color: #0d3978;\"><span style=\"font-size: 14px;\"><strong>\u5fae\u751f\u7269\u7fa4\u4e0e\u5065\u5eb7\u00a0<\/strong> \u00a0<\/span><\/span><\/p>\n<p><span style=\"font-size: 14px;\">\u5fae\u751f\u7269\u7fa4\u5bf9\u7ef4\u6301\u4eba\u4f53\u5065\u5eb7\u81f3\u5173\u91cd\u8981\uff0c\u5b83\u4eec\u751a\u81f3\u53ef\u4ee5\u770b\u4f5c\u662f\u4e00\u4e2a\u5355\u72ec\u7684\u4eba\u4f53\u5668\u5b98\u3002\u76ee\u524d\u7684\u79d1\u5b66\u7814\u7a76\u8ba4\u4e3a\u80a0\u9053\u5fae\u751f\u7269\u4e0e\u591a\u79cd\u75be\u75c5\u6709\u5173\u8054\uff0c\u4f8b\u5982\u708e\u75c7\u6027\u80a0\u75c5\uff08Inflammatory bowel disease\uff09\u3001 \u574f\u6b7b\u6027\u5c0f\u80a0\u7ed3\u80a0\u708e\u3001\u7279\u5e94\u6027\u75be\u75c5\uff08Atopic disease\uff09,\u3001\u4e00\u578b\u7cd6\u5c3f\u75c5\uff08T1DM\uff09\u3001 \u81ea\u95ed\u75c7\uff08Autistic spectrum disorder\uff09\u7b49\u3002\u80a0\u9053\u5fae\u751f\u7269\u627f\u62c5\u62b5\u5fa1\u75c5\u539f\u4f53\uff0c\u5408\u6210\u7ef4\u751f\u7d20(\u4f8b\u5982\u7ef4\u751f\u7d20K\u548c\u90e8\u5206B\u65cf\u7ef4\u751f\u7d20\u7531\u80a0\u9053\u83cc\u7fa4\u5408\u6210)\uff0c\u514d\u75ab\u7cfb\u7edf\u53d1\u5c55\uff0c\u53c2\u4e0e\u8425\u517b\u4ee3\u8c22\uff0c\u8c03\u8282\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u7b49\u4f5c\u7528\u3002\u53ef\u4ee5\u8bf4\uff0c\u6ca1\u6709\u5065\u5eb7\u7684\u80a0\u9053\u5fae\u751f\u7269\u7fa4\uff0c\u4eba\u4f53\u5c31\u51e0\u4e4e\u65e0\u6cd5\u6b63\u5e38\u8fd0\u4f5c\u3002<\/span><\/p>\n<p><span style=\"color: #0d3978;\"><strong><span style=\"font-size: 14px;\">\u80a0\u9053\u5fae\u751f\u7269\u7684\u7814\u7a76\u65b9\u5f0f<\/span><\/strong><\/span><\/p>\n<p><span style=\"font-size: 14px;\">\u80a0\u9053\u5fae\u751f\u7269\u5927\u591a\u6570\u65f6\u5019\u90fd\u901a\u8fc7\u975e\u4fb5\u5165\u7684\u65b9\u5f0f\u83b7\u53d6\u6837\u672c\uff0c\u7531\u7814\u7a76\u8005\u5206\u53d1\u53d7\u8bd5\u8005\u7caa\u4fbf\u6536\u96c6\u5668\u548c\u4fdd\u5b58\u5668\uff0c\u8ba9\u53d7\u8bd5\u4eba\u5458\u81ea\u884c\u5728\u5bb6\u6536\u96c6\u7caa\u4fbf\u3002\u82e5\u901a\u8fc716s RNA\u65b9\u6cd5\u5bf9\u80a0\u9053\u5fae\u751f\u7269\u8fdb\u884c\u5206\u7c7b\u548c\u9274\u5b9a\uff0c\u5219\u9700\u7528\u68c9\u7b7e\u5728\u5395\u7eb8\u4e0a\u62ed\u53d6\u5c11\u91cf\u7caa\u4fbf\uff0c\u800c\u5168\u57fa\u56e0\u7ec4\u9e1f\u67aa\u6d4b\u5e8f\u5219\u9700\u8981\u7ea61g\u7684\u6837\u672c\u91cf\u3002\u6536\u96c6\u7684\u6837\u672c\u901a\u8fc7\u6d78\u5165\u7a33\u5b9a\u7f13\u51b2\u6db2\u6216\u51b7\u85cf\u51b7\u51bb\u8fdb\u884c\u4fdd\u5b58\uff0c\u8fd0\u9001\u5230\u4e13\u4e1a\u5b9e\u9a8c\u5ba4\u540e\u518d\u8fdb\u884c\u4e0b\u4e00\u6b65\u68c0\u6d4b\u3002 \u4e00\u822c\u8ba4\u4e3a\uff0c-80\u00b0C\u65e0\u6c27\u6216\u6709\u6c27\u73af\u5883\u51b7\u51bb\u4fdd\u5b58\u80fd\u6700\u957f\u65f6\u95f4\u7684\u7ef4\u6301\u6837\u54c1\u7a33\u5b9a\u6027\uff0c\u4fdd\u5b58\u65f6\u9650\u53ef\u8fbe\u6570\u6708\u751a\u81f3\u6570\u5e74\u3002<\/span><\/p>\n<p><span style=\"font-size: 14px;\">\u9664\u4e86\u7caa\u4fbf\u6837\u672c\u6536\u96c6\u4e4b\u5916\uff0c\u7814\u7a76\u8005\u4e00\u822c\u8fd8\u4f1a\u8981\u6c42\u53d7\u8bd5\u8005\u6839\u636eBristol Stool Chart\u8bb0\u5f55\u7caa\u4fbf\u5916\u89c2\u548c\u5bc6\u5ea6\u4ee5\u53cd\u6620\u7caa\u4fbf\u5728\u80a0\u9053\u5185\u7684\u8fd0\u8f6c\u65f6\u95f4\u3002Bristol Stool Chart\u8bc4\u4ef7\u8868\u6839\u636e\u7caa\u4fbf\u7684\u8f6f\u786c\u7a0b\u5ea6\u4ece\u6570\u503c1\u81f37\u6392\u5e8f\uff0c 1\u4e3a\u6700\u786c\uff0c7\u4e3a\u6700\u8f6f\u3002\u786c\u5757\u72b6\u7caa\u4fbf\u901a\u8fc7\u80a0\u9053\u65f6\u95f4\u8f83\u957f\uff0c\u6216\u8bb8\u5b58\u5728\u4e25\u91cd\u4fbf\u79d8\uff1b\u67d4\u8f6f\u7684\u7caa\u4fbf\u901a\u8fc7\u80a0\u9053\u65f6\u95f4\u77ed\uff1b\u6c34\u6837\u7caa\u4fbf\u5219\u8868\u793a\u5b58\u5728\u8179\u6cfb\u3002\u00a0<\/span><\/p>\n<p><span style=\"color: #0d3978;\"><strong><span style=\"font-size: 14px;\">\u5fae\u751f\u7269\u7fa4\u7684\u5f71\u54cd\u56e0\u7d20\u00a0<\/span><\/strong><\/span><\/p>\n<p><span style=\"font-size: 14px;\">\u5fae\u751f\u7269\u7fa4\u4e0d\u4ec5\u4ec5\u53d7\u4e2a\u4eba\u57fa\u56e0\u578b\u5f71\u54cd\uff0c\u5916\u5728\u56e0\u7d20\u5305\u62ec\u598a\u5a20\u5468\u671f\uff0c\u751f\u4ea7\u65b9\u5f0f\uff08\u987a\u4ea7\u6216\u5256\u8179\u4ea7\uff09\uff0c\u5582\u517b\u65b9\u5f0f\uff0c\u5b55\u6bcd\u8425\u517b\u72b6\u6001\uff0c\u4ee5\u53ca\u6297\u751f\u7d20\u7684\u4f7f\u7528\u90fd\u4f1a\u5bf9\u80a0\u9053\u5fae\u751f\u7269\u4ea7\u751f\u5f71\u54cd\u3002\u4e0d\u540c\u5e74\u9f84\u9636\u6bb5\u7684\u80a0\u9053\u5fae\u751f\u7269\u7ec4\u6210\u4e5f\u6709\u6240\u4e0d\u540c\uff0c\u4f46\u662f\u73b0\u5728\u7684\u7814\u7a76\u4e00\u822c\u8ba4\u4e3a\u57283\u5c81\u5de6\u53f3\uff0c\u4eba\u4f53\u7684\u4e3b\u5bfc\u83cc\u7fa4\u5df2\u7ecf\u5f62\u6210\uff0c\u540e\u7eed\u7684\u5f71\u54cd\u56e0\u7d20\u4e3b\u8981\u4e3a\u751f\u6d3b\u65b9\u5f0f\u3001\u751f\u6d3b\u73af\u5883\u3001\u548c\u996e\u98df\u4e60\u60ef\u3002<\/span><\/p>\n<p><span style=\"color: #0d3978;\"><strong><span style=\"font-size: 14px;\">\u80a0\u9053\u5fae\u751f\u7269\u7684\u5e94\u7528<\/span><\/strong><\/span><\/p>\n<p><span style=\"font-size: 14px;\">\u5c3d\u7ba1\u4e0d\u5c11\u79d1\u5b66\u7814\u7a76\u8ba4\u4e3a\u80a0\u9053\u5fae\u751f\u7269\u548c\u591a\u79cd\u75be\u75c5\u5173\u8054\uff0c\u4f46\u662f\u5177\u4f53\u81f4\u75c5\u673a\u7406\u548c\u6cbb\u75c5\u624b\u6bb5\u5c1a\u65e0\u5b9a\u8bba\u3002\u552f\u4e00\u5f97\u5230\u786e\u8ba4\u7684\u662f\u76f8\u5bf9\u4e8e\u5e38\u7528\u7684\u4e07\u53e4\u9709\u7d20\u6cbb\u7597\uff0c\u5229\u7528\u80a0\u9053\u5fae\u751f\u7269\u79fb\u690d\uff08FMT\uff09\u6cbb\u7597\u96be\u6108\u548c\u6613\u590d\u53d1\u7684\u8270\u96be\u68ad\u83cc\u611f\u67d3\uff08CDI\uff09\u6709\u660e\u663e\u4f18\u52bf\uff08\u5eb7\u590d\u7387\uff1a60% vs. 90%\uff09\u3002<\/span><\/p>\n<p><span style=\"font-size: 14px;\">\u7528\u4e8e\u79fb\u690d\u7684\u80a0\u9053\u5fae\u751f\u7269\u6765\u81ea\u8eab\u4f53\u5065\u5eb7\u7684\u6350\u732e\u8005\u3002\u6350\u8d60\u524d\u4e00\u822c\u4f1a\u68c0\u6d4b\u6350\u732e\u8005\u662f\u5426\u5b58\u5728HIV\u548c\u809d\u708e\u75c5\u6bd2\u611f\u67d3\uff0c\u7caa\u4fbf\u662f\u5426\u5b58\u5728\u7ec6\u83cc\u3001\u75c5\u6bd2\u548c\u5bc4\u751f\u866b\u611f\u67d3\uff0c\u5728\u786e\u8ba4\u6350\u732e\u8005\u7b26\u5408\u5065\u5eb7\u6807\u51c6\u540e\u624d\u4f1a\u63a5\u53d7\u5176\u6350\u8d60\u3002\u6350\u732e\u7684\u7caa\u4fbf\u6db2\u5316\u548c\u8fc7\u6ee4\u540e\u4e00\u822c\u901a\u8fc7\u7ed3\u80a0\u955c\u9001\u5165\u7ed3\u80a0\uff0c\u53e6\u5916\u4e5f\u53ef\u4ee5\u901a\u8fc7\u7ba1\u9972\uff0c\u704c\u80a0\uff0c\u548c\u80f6\u56ca\u7684\u65b9\u5f0f\u9001\u5165\u7ed3\u80a0\u5185\u3002#\u5728\u7f8e\u56fd\uff0c\u6210\u529f\u6350\u732e\u4e00\u4efd\u5408\u683c\u7caa\u4fbf\uff0c\u53ef\u4ee5\u5f97\u5230\u7ea640\u7f8e\u91d1\u7684\u62a5\u916c#<\/span><\/p>\n<p><span style=\"color: #0d3978;\"><strong><span style=\"font-size: 14px;\">\u603b\u7ed3\uff1a<\/span><\/strong><\/span><\/p>\n<p><span style=\"font-size: 14px;\">\u80a0\u9053\u5fae\u751f\u7269\u65e0\u7591\u662f\u8fd1\u5e74\u6765\u70ed\u95e8\u7814\u7a76\u8bdd\u9898\u4e4b\u4e00\uff0c\u800c\u4e14\u5927\u91cf\u7684\u7814\u7a76\u8868\u660e\u9006\u8f6c\u80a0\u9053\u5fae\u751f\u7269\u7d0a\u4e71\u5bf9\u75be\u75c5\u7684\u7ba1\u7406\u548c\u6cbb\u7597\u5e76\u975e\u4e00\u7eb8\u7a7a\u8c08\u3002\u5f53\u524d\u7684\u7814\u7a76\u7126\u70b9\u5305\u62ec\uff1a\u5982\u4f55\u5e73\u8861\u80a0\u9053\u5fae\u751f\u7269\uff1b\u76ca\u751f\u83cc\u548c\u76ca\u751f\u5143\u5bf9\u80a0\u9053\u5fae\u751f\u7269\u7684\u5f71\u54cd\uff1b\u6297\u751f\u7d20\u76ee\u6807\u6cbb\u7597\uff08\u5229\u7528\u6297\u751f\u7d20\u6291\u5236\u6709\u5bb3\u83cc\u7fa4\uff0c\u4fc3\u8fdb\u6709\u76ca\u83cc\u7fa4\u751f\u957f\uff09\uff1b\u5229\u7528\u80a0\u9053\u5fae\u751f\u7269\u8bca\u65ad\u548c\u6cbb\u7597\u75be\u75c5\uff0c\u4ee5\u53ca\u5177\u4f53\u7684\u81f4\u75c5\u673a\u5236\u7b49\u7b49\u3002\u5c3d\u7ba1\u5f53\u524d\u80a0\u9053\u5fae\u751f\u7269\u7814\u7a76\u4ecd\u5904\u4e8e\u8d77\u6b65\u9636\u6bb5\u4e14\u6709\u5927\u91cf\u7684\u95ee\u9898\u6709\u5f85\u89e3\u7591\uff0c\u4f46\u672a\u6765\u5229\u7528\u80a0\u9053\u5fae\u751f\u7269\u76d1\u6d4b\uff0c\u9884\u9632\u4ee5\u53ca\u6cbb\u7597\u75be\u75c5\u503c\u5f97\u671f\u8bb8\u3002<\/span><\/p>\n<p><span style=\"font-size: 14px;\">#\u5c0f\u77e5\u8bc6\uff1a\u7caa\u4fbf\u6837\u672c\u9664\u4e86\u53ef\u4ee5\u8fdb\u884c\u5fae\u751f\u7269\u7fa4\u68c0\u6d4b\u4ee5\u5916\uff0c\u8fd8\u662f\u6d88\u5316\u9053\u75be\u75c5\u7684\u5e38\u89c1\u8f85\u52a9\u8bca\u65ad\u624b\u6bb5\u3002\u901a\u8fc7\u8bc4\u4f30\u7caa\u4fbfpH\u503c\uff0c\u9690\u8840\uff0c\u8102\u80aa\uff0c\u767d\u7ec6\u80de\uff0c\u80c6\u6c41\u9178\uff0c\u5176\u4ed6\u6b8b\u5b58\u8425\u517b\u7269\u8d28\u4ee5\u53ca\u5fae\u751f\u7269\u6765\u8bc4\u4f30\u53d7\u8bd5\u8005\u662f\u5426\u5b58\u5728\u611f\u67d3\uff0c\u8425\u517b\u5438\u6536\u4e0d\u826f\uff0c\u6216\u764c\u75c7\u7684\u98ce\u9669\u3002<\/span><\/p>\n<p><span style=\"color: #0d3978;\"><strong><span style=\"font-size: 14px;\">\u53c2\u8003\u6587\u732e\uff1a<\/span><\/strong><\/span><\/p>\n<p><span style=\"font-size: 14px;\">1. Yadav M, Verma MK, Chauhan NS. A review of metabolic potential of human gut microbiome in human nutrition. Archives of Microbiology, 2018, 200(2):203-217.<br \/>2. Vogtmann E, Chen J, Amir A, et al. Comparison of collection methods for fecal samples in microbiome studies. american journal of epidemiology, 2017, 185(2):115-123.<br \/>3. Ursell LK, Metcalf JL, Parfrey LW, Knight R. Defining the human microbiome. Nutritonn Review, 2012, 70(Suppl 1): S38\u2013S44.<br \/>4. Blum HE. The human microbiome, Advances in Medical Sciences, 2017 (62), 414\u2013420.<br \/>5. Lee CH, Steiner T, Petrof EO, et al. Frozen vs fresh fecal microbiota transplantation and clinical resolution of diarrhea in patients with recurrent Clostridium difficile infection: a randomized clinical trial. JAMA. 2016;315(2):142-149.<br \/>6. Vindigni SM, Surawicz CM. Fecal microbiota transplantation. Gastroenterology Clinical North America, 2017(46),171\u2013185.\u00a0<br \/>7. Cani PD. Human gut microbiome: hopes, threats and promises. Gut 2018;67:1716\u20131725.\u00a0<br \/>8. Cresci GA. The Gut Microbiome: What we do and don\u2019t know. Nutrition Clinical Practice, 2015, 30(6), 734 \u2013746.<br \/>9. Milani C, Duranti S, Bottacini F, et al. The first microbial colonizers of the\u00a0human gut: composition, activities, and health implications of the infant gut microbiota. Microbiology and Molecular Biology Reviews, 2017, 8;81(4). pii: e00036-17.\u00a0<br \/>10. Thomas V, Clark J, Dore J. Fecal microbiota analysis: an overview of sample collection methods and sequencing strategies. Future Microbiology. 2015;10(9):1485-504.<br \/>11. Stool Analysis. 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