{"id":5092,"date":"2022-03-15T09:58:36","date_gmt":"2022-03-15T01:58:36","guid":{"rendered":"https:\/\/www.merieuxnutrisciences.com.cn\/?p=5092"},"modified":"2022-04-25T14:06:36","modified_gmt":"2022-04-25T06:06:36","slug":"stability-and-period-after-opening-pao-2","status":"publish","type":"post","link":"https:\/\/www.merieuxnutrisciences.com.cn\/?p=5092&lang=en","title":{"rendered":"Stability and Period After Opening (PAO)"},"content":{"rendered":"\n<div class=\"wp-block-media-text alignwide is-stacked-on-mobile\"><figure class=\"wp-block-media-text__media\"><\/figure><div class=\"wp-block-media-text__content\">\n<h3 id=\"to-ensure-that-your-products-meet-quality-standards-when-stored-under-proper-conditions-a-safety-and-stability-assessment-is-required-merieux-nutrisciences-provides-a-full-complement-of-customizable-analytical-methods-in-order-to-respond-to-customer-requirements-on-a-case-by-case-basis\">To ensure that your products meet quality standards when stored under proper conditions, a safety and stability assessment is required. M\u00e9rieux NutriSciences provides a full complement of customizable analytical methods in order to respond to customer requirements on a case-by-case basis.&nbsp;<\/h3>\n\n\n\n<p>Cosmetic and personal care products are made using a wide variety of materials and formulations, making it impossible to establish a standard protocol applicable to all. Regulators recommend that stability tests be adapted according to the type of product and intended use, including reasonably foreseeable storage conditions.<\/p>\n\n\n\n<p>Our stability assessments cover the following parameters and are based on international guidelines:<\/p>\n\n\n\n<ul><li><strong>Organoleptic and sensory properties<\/strong>: appearance, color, odor and flavor, as applicable<\/li><li><strong>Physical-chemical properties<\/strong>: pH value, viscosity, density and, if necessary, ingredient formulation<\/li><li><strong>Microbiological properties<\/strong>: microbial count and preservation challenge test<\/li><li><strong>Monitoring of active substances<\/strong>: UV filters, antioxidants, antimicrobial agents, etc.<\/li><li><strong>Screening of aromatic substances to determinate qualitative and quantitative fragrance alteration<\/strong><\/li><\/ul>\n\n\n\n<p>Accelerated stability, also known as normal or exploratory stability, can help to predict a product\u2019s stability and useful shelf life, as well as the compatibility of the formulation with the materials with which it will enter into contact (<em>link to Cosmetic packaging<\/em>).<\/p>\n\n\n\n<p>Other specific storage conditions that can be applied are:<\/p>\n\n\n\n<ul><li>Period after opening (PAO): simulation of useful lifespan<\/li><li>Thermal shock, with protocols that provide alternate cycles at different temperatures<\/li><li>Light stability (Xenon test) of finished products<\/li><li>Photostability of chemical UV filters<\/li><\/ul>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>To ensure that your products meet quality standards whe [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[441],"tags":[],"modified_by":"amyadmin","_links":{"self":[{"href":"https:\/\/www.merieuxnutrisciences.com.cn\/index.php?rest_route=\/wp\/v2\/posts\/5092"}],"collection":[{"href":"https:\/\/www.merieuxnutrisciences.com.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.merieuxnutrisciences.com.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.merieuxnutrisciences.com.cn\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.merieuxnutrisciences.com.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5092"}],"version-history":[{"count":2,"href":"https:\/\/www.merieuxnutrisciences.com.cn\/index.php?rest_route=\/wp\/v2\/posts\/5092\/revisions"}],"predecessor-version":[{"id":5629,"href":"https:\/\/www.merieuxnutrisciences.com.cn\/index.php?rest_route=\/wp\/v2\/posts\/5092\/revisions\/5629"}],"wp:attachment":[{"href":"https:\/\/www.merieuxnutrisciences.com.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5092"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.merieuxnutrisciences.com.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5092"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.merieuxnutrisciences.com.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5092"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}